Gene information
Official symbol HSPA4
Official full name heat shock protein family A (Hsp70) member 4
Gene type protein-coding gene
Chromosome5q31.1
Alias symbolHS24/P52; HSPH2
Gene familyHeat shock 70kDa proteins
Resources
Entrez Gene 3308
HGNC HGNC:5237
Ensembl ENSG00000170606
Vega OTTHUMG00000129012
UCSC uc003kyj.4
GO terms: 6 records
GO Description Category LogP Number of genes Detail
GO:0006457 protein folding GO Biological Processes -2.73896005 9 More
GO:0006986 response to unfolded protein GO Biological Processes -2.24519355 6 More
GO:0007005 mitochondrion organization GO Biological Processes -2.05283627 29 More
GO:0035966 response to topologically incorrect protein GO Biological Processes -3.19318664 8 More
GO:0051131 chaperone-mediated protein complex assembly GO Biological Processes -2.54615630 3 More
GO:0140657 ATP-dependent activity GO Molecular Functions -2.60810192 16 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04612 Antigen processing and presentation KEGG Pathway -2.44266926 5 More
hsa05417 Lipid and atherosclerosis KEGG Pathway -33.3876857 40 More
Drug-Gene interaction
view
Related drugs: 31 records
Drug name Interaction type Source PMID View
bortezomib NCI 16846475 view
celecoxib NCI 16646082 view
chlorpromazine NCI 12857801 view
cisplatin NCI 11478701 view
cytarabine NCI 12530536 view
deferoxamine NCI 11579132 view
enalapril NCI 12047041 view
epoetin alfa NCI 15943180 view
gossypol NCI 2193225 view
haloperidol NCI 9864262 view
heparin NCI 7548155 view
hydralazine NCI 12047041 view
ifosfamide NCI 12530536 view
isoproterenol NCI 8047983 view
ketanserin NCI 9864262 view
lithium NCI 127327321617952416797496 view
midostaurin NCI 17032922 view
minnelide TTD view
nifedipine NCI 7770620 view
nimesulide NCI 9645681 view
phenylephrine NCI 8047983 view
photofrin NCI 8625311 view
pioglitazone NCI 12871756 view
puromycin NCI 317055536644991986403 view
ranitidine NCI 11523209 view
sodium chloride NCI 8724993 view
thiabendazole NCI 11226373 view
urea NCI 7548155 view
verapamil NCI 12857801 view
wortmannin NCI 16979664 view
zalcitabine NCI 10591146 view
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
heat shock 70 kDa protein 4 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Dybdahl B et al. Heart. 2005
heat shock 70 kDa protein 4 proteomics poor predictor acute myocardial infarction[diagnosis] acute myocardial infarction Amanvermez R et al. Bosn J Basic Med Sci. 2012
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